CTX-M-15-producing Enterobacteriaceae isolates causing bloodstream infections at the Beni-Messous hospital in Algiers (Algeria)

Abstract

The purpose of this was to characterize the ESBL produced by multiresistant Enterobacteriaceae isolates and their sensitivity profile recovered from children admitted at the pediatric ward of BeniMessous hospital (Algeria) during the period May 2008 to August 2010 at the Beni-Messous hospital in Algiers (Algeria). 31 ESBL-producing Enterobacteriaceae isolates were tested towards 21 antimicrobial agents. PCR were used to determine the genetic determinants responsible for the ESBL phenotypes. All isolates were found resistant to ticarcillin, ticarcillin-clavulanate, piperacillin, amoxicillin-clavulanate, cefuroxime, aztreonam, ceftazidime, cefotaxime, cefepime and cefpirome. PCR and DNA sequencing identified these extended-spectrum β-lactamases as CTX-M-15 in all isolates.